Rodent zero maze

Rodent zero maze, as known as elevated zero maze, is a modification of the elevated plus maze model of anxiety in rodents. The novel design comprises an elevated annular platform with two opposite, enclosed quadrants and two open quadrants, removing any ambiguity in the interpretation of the time spent in the central square of the traditional design and allowing uninterrupted exploration. Results of the study indicated that elevated zero maze offered a better animal model to study antianxiety activity, when compared with elevated plus maze and mirror chamber.